Recombinant Human Neuropilin-2 Protein

时间:2024年04月25日 来源:

SARS-CoV-2, which causes the global pandemic coronavirus disease 2019 (Covid-19), belongs to a family of viruses known as coronaviruses that also include MERS‑CoV and SARS-CoV-1. Coronaviruses are commonly comprised of four structural proteins: Spike protein (S), Envelope protein (E), Membrane protein (M) and Nucleocapsid protein (N). The SARS-CoV-2 S protein is a glycoprotein that mediates membrane fusion and viral entry. The S protein is homotrimeric, with each ~180-kDa monomer consisting of two subunits, S1 and S2 .The RBD of SARS-CoV-2 binds a metallopeptidase, angiotensin-converting enzyme 2 (ACE-2). Before binding to the ACE-2 receptor, structural analysis of the S1 trimer shows that only one of the three RBD domains is in the "up" conformation. This is an unstable and transient state that passes between trimeric subunits but is nevertheless an exposed state to be targeted for neutralizing antibody therapy. Polyclonal antibodies to the RBD of the SARS-CoV-2 protein have been shown to inhibit interaction with the ACE-2 receptor, confirming RBD as an attractive target for vaccinations or antiviral therapy.  rTEV是一种用来切除融合蛋白上亲和标签的常用工具酶,具有很强的位点特异性,严格识别七氨基酸序列。Recombinant Human Neuropilin-2 Protein,His Tag

Recombinant Human Neuropilin-2 Protein,His Tag,标准物质

CD40,alsoknownasTNFRSF5,isa45-50kDatypeItransmembraneglycoproteinmemberoftheTNFreceptorsuperfamily.MaturehumanCD40consistsofa173aminoacid(aa)extracellulardomain,atransmembranedomain,anda62aacytoplasmicdomain.CD40servesmultiplefunctionsinbothhematopoieticandepithelialcancersandisatargetfortumorimmunotherapy.DysregulationofCD40/CD40LigandexpressionandinteractionscontributestotheimmunedeficiencyassociatedwithHIVinfectionandAIDS.Itisalsoimplicatedinthepathologyofmultiplecardiovasculardiseasesincludingatherosclerosis,atherothrombosis,andrestenosis.产品性质别名CD40;CD40Lreceptor;TNFRSF5;CD40antigen;CD40molecule;CDw40;MGC9013;UniprotNo.P25942表达区间及表达系统RecombinantBiotinylatedHumanCD40/TNFRSF5ProteinisexpressedfromHEK293CellswithHistagandAvitagattheC-terminal.ItcontainsGlu21-Arg193.分子量Approximately22.1kDa.Duetoglycosylation,theproteinmigratesto35-40kDabasedonTris-BisPAGEresult.纯度>95%asdeterminedbySDS-PAGEandHPLC.活性Recombinant Human APOE3/Apolipoprotein E Protein,hFc TagAFGF在调节细胞存活,细胞分裂,血管生成,细胞分化和细胞迁移中起重要作用。

Recombinant Human Neuropilin-2 Protein,His Tag,标准物质

CD19蛋白在B细胞和体液免疫反应中起着作用。成熟B细胞对抗原刺激、胚芽中心发育和抗体亲和性成熟的反应能力是必需的。CD19已成为血液学和实体的有前途的靶点。产品性质同义词CD19;B4;CVID3;Leu-12;MGC12802工会编号P15391来源生化重组人CD19蛋白表达于HK293细胞,标记于C-端。它含有金属1-Lys291。分子量重组cd19由283个氨基酸组成,预测分子质量为31.6kda。纯洁90%由社会发展秘书处----政策和两性平等局确定。内用Lal法测定每一种蛋白质。公式化用0.22腔形过滤液对PBS进行冻干。冻干前添加5%-8%海藻糖、甘露醇和0.01%TWEen80作为保护剂。重建离心管打开前。建议将其重组为100克/毫升以上的浓度。在蒸馏水中溶解冻干蛋白。

糖苷酶F(PNGaseF)是一种酰胺水解酶,经过和平空间站伊丽莎菌克隆,主要由脑膜炎脓杆菌等革兰氏阴性菌分泌。N-糖苷酶F(PNGaseF)在酵母中重组表达(比活性:100000U/mL),可以裂解由天冬酰胺连接的高甘露糖、杂合和复杂的寡糖糖蛋白。PNGaseF的切割位点为糖蛋白内侧N-乙酰葡萄糖胺(GlcNAc)和天冬酰氨残基之间的酰胺键,同时将酶解后蛋白上的天冬氨酰转化为天冬氨酸。本产品带his标签,常应用于抗体及其相关蛋白完全去糖基化。另外,我司还提供其他类型的糖苷酶,包括酵母重组表达的N-糖苷酶F(比活性:750000U/mL),内切糖苷酶H,内切糖苷酶S。产品信息产品性质中文别名(Chinesesynonym)N-糖酰胺酶F;N-糖苷酶F英文别名(Englishsynonym)PNGaseF来源(Source)酵母重组表达分子量(Molecularweight)36kDa比活性(Specificactivity)100000U/mL缓冲液组分(Buffer)20mMTris-HClpH7.5,50mMNaCl,5mMEDTA,50%GlycerolUbcH5a/UBE2D1具有一个保守的E2催化结构域,该结构域含有一个活性位点半胱氨酸残基。

Recombinant Human Neuropilin-2 Protein,His Tag,标准物质

透明质酸酶活力单位(Unitdefinition)基于USP透明质酸酶参照标准,即每分钟在37℃,pH5.7的2mL反应液中引起OD6000.330个变化定义为一个活力单位。抑制剂(Inhibitor)Fe2+,Fe3+,Zn2+,Cu2+,肝素,金精三羧酸,硫酸,硝酸,乙酰化透明质酸,硫酸纤维素酯,胆汁等结构式(Structure)运输和保存方法冰袋运输。-20℃保存,两年有效。溶液配制溶于0.02MPBS(pH7.0),含77mMNaCl和0.01%BSA,浓度为1mg/mL。现配现用。该产品储存液不稳定,使用时建议现配现用。为了您的安全和健康,请穿实验服并戴一次性手套操作。RANTES是对单核细胞,记忆T细胞(CD4+/CD45RO),嗜碱性粒细胞和嗜酸性粒细胞的趋化剂。Recombinant Mouse LILRB4/CD85k/ILT3 Protein,His Tag

在体内,活化的X因子(Factor Xa)切割凝血酶原,释放出活性肽并将凝血酶切割成具有催化活性的α-凝血酶。Recombinant Human Neuropilin-2 Protein,His Tag

α-凝血酶(α-Thrombin)产品性质中文别名(Chinesesynonym)α-凝血酶;IIa因子;英文别名(Englishsynonym)α-Thrombin;FactorIIaCAS号(CASNO.)9002-04-4分子量(Molecularweight)37000daltons活力(Activity)≥3091.00NIHU/mg缓冲液组分(Buffer)50mMSodiumCitrate/0.2MNaCl/0.1%PEG-8000/pH6.5含量(Totalprotein)0.324mg运输和保存方法粉末冰袋运输,2-8℃保存;配好的液体,请于≤-60℃保存。使用方法(酶切体系)产品溶于水,配成的1000U/ml储存液,根据使用量分配于不同的离心管中,冻存于−20℃保存,凝血酶对不同的融合蛋白切割效率是不一样的,首先要进行小量切割试验。比如固定融合蛋白10ug,加不同量的凝血酶(如0.1U,0.2U,0.5U,1U等),在不同的温度(如4度,16度,室温或37度等)下进行试验。Recombinant Human Neuropilin-2 Protein,His Tag

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